|Author||DOI||Year||Country||Dates||Aim of the study||Study Design||Type of rehabilitation service||Research Question||LFRI||COVID-19 Phases||Population||N° of participants||Clinical presentation||Intervention||Comparator||Outcomes||Adverse events||Diagnostic test||Sensitivity||Specifity||Types of validity||Attributes of reliability||Main findings|
|Burns SP||10.1038/s41393-020-0529-0||2020||USA||March 9th - June 30th, 2020||To describe case fatality of COVID-19 infection in Veterans with SCI/D||Analytical: Cohort study||Specialized postacute rehabilitation||Epidemiology - Prevalence||N/A||Acute, post-acute, late-onset, or permanent on a pre-existing health condition||Veterans with SCI/D with diagnosis of COVID-19||140||N/R||N/A||Veterans with SCI/D without diagnosis fo COVID-19||Case fatality rate||N/A||N/A||N/A||N/A||N/A||N/A||The SCI/D Veteran case fatality rate with COVID-19 was 19%; it was 2.4 times the rate observed in the non-SCI/D Veteran population with an absolute rate that is 11% greater (95% CI: 5–19%; Z score = 4.8; p < 0.0002).|
|Curci C||10.23736/S1973-9087.20.06339-X||2020||Italy||March 10th - April 15th, 2020||To characterize pulmonary function and disability status and to propose an early rehabilitation protocol in a cohort of post-acute COVID-19 patients admitted to a Rehabilitation Unit.||Analytical: Cross-sectional study||Specialized postacute rehabilitation||Epidemiology - Clinical presentation||Respiratory structures (s430) and related functions (Respiration b440-455)||Post-acute||COVID-19 patients||32||Most patients needed respiratory supports (mainly nasal cannula and Venturi Mask) with a sustained FiO2 to maintain a good peripheral oxygen saturation. Moreover, the majority was bedridden and suffered from dyspnoea and shortness of breath even for minimal activities||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||
|Di Stefano V||10.1007/s00415-020-10064-6||2020||Italy||April 20th - May 4th, 2020||To quantify the reduction of PA in patients with NMD due to lockdown, and its impact on quality of life||Analytical: Cross-sectional study||N/A||Epidemiology - Prevalence||N/A||N/A||Patients with pre-existing NMD and healthy age-matched controls||NMD group= 149; healthy controls= 119||N/A||N/A||N/A||Levels of PA measured by IPAQ-SF as energy expenditure (MET–minutes/week), both before and in the last 7 days of the quarantine. The distribution of MET was calculated for different levels of PA intensity (vigorous-intensity PA; moderate-intensity PA; moderate-to-vigorous PA; walking activity) in all subjects. SF-12 was also administered by telephone to NMD group .||N/A||N/A||N/A||N/A||N/A||N/A||In healthy controls, a significant reduction of PA was reported during quarantine compared to before quarantine for vigorous-intensity, moderate-intensity and moderate-to-vigorous intensity and total PA levels, and for walking activity. In NMD, a significant reduction of PA was reported for walking activity, moderate-to-vigorous and total PA levels, while no difference was found for vigorous-intensity and moderate-intensity PA. Furthermore, NMD showed reduced scores for SF12.|
|Diaz-Segarra N||10.1097/PHM.0000000000001532||2020||USA||N/R||To report clinical findings of four COVID-19 patients that developed acute ischemic stroke||Descriptive: Case Series||Rehabilitation in acute care||Epidemiology - Clinical presentation||Nervous system structures (s1) and related functions (Neuromusculoskeletal and movement related functions b7)||Acute||COVID-19 patients||4||Patient 1: Dysarthria; left hemiparesis, and reduced LOC + cough, fever, chills; deceased on day 3; Patient 2: Aphasia, facial droop; right hemiparesis, sensory deficit, complete hemianopsia + None symptoms of COVID-19; discharged home on day 9; Patient 3: Reduced LOC + Shortness of breath, fevers; ARDS; sepsis, MOF, deceased on day 42; Patient 4: Reduced LOC + Cough, SOB, diarrhea; ARDS, sepsis, MOF, discharged to rehabilitation on day 29.||Patient 1: Mechanical thrombectomy, aspirin; Patient 2: IV t-PA, mechanical thrombectomy, aspirin; Patient 3: Aspirin; Patient 4: Aspirin||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||This case series highlights that COVID-19 ischemic strokes had a heterogeneuos clinical presentation with an unknown duration of the COVID-19 related prothrombotic state. Therefore, the authors concluded that the physiatric awareness of this prothrombotic state is mandatory, taking into account the increased incidence of ischemic strokes in COVID-19 patients referred to rehabilitation units.|
|Gualtieri P||10.3390/ijms21134670||2020||Italy||March 19th - April 27th, 2020||To evaluate the differences in body composition during a ICU hospitalization in overall, lean, and obese COVID-19 patients.||Analytical: Cohort study||N/A||Epidemiology - Natural history/Determining and modifying factors||Any other body structure and function-generic (s/b)||Acute||COVID19 patients||30 (13 lean and 17 obese patients)||N/R||Chest CT within 24 hours and about 20 days later||N/A||Differences in body composition and liver composition during ICU hospitalization (assessed by chest CT)||N/A||N/A||N/A||N/A||N/A||N/A||Subscapular thickness, suprailiac thickness, sum thickness, body density, FM%, and waist circumference were statically increased in the obese group compared to the lean group. Liver attenuation and liver/spleen ratio were statistically reduced in the obese group compared to the lean group. These findings could be co-caused by COVID-19, prolonged bed rest, and a low-grade inflammation typical of obesity.|
|Halpin SJ||10.1002/jmv.26368||2020||UK||May-June 2020||To describe the symptoms and rehabilitation needs of COVID-19 patients after discharge||Analytical: Cross-sectional study||Rehabilitation services at home||Epidemiology - Prevalence||Respiratory structures (s430) and related functions (Respiration b440-455)||Post-acute||COVID-19 patients 4 weeks after hospital discharge||100||N/A||Telephonic survey||N/A||Prevalence of post-discharge symptoms||N/A||N/A||N/A||N/A||N/A||N/A||The most common symptom reported was fatigue (72% of post ICU patients; 60.3 % of hospitalized patients), followed by breathlessness (65.6% in ICU group; 42.6% in hospitalized group) and psychological distress (46.9% in ICU group; 23.5% in hospitalized group). There was a clinically significant drop in EQ5D in 68.8% participants in the ICU group and in 45.6% of participants in the ward group. The authors recommend planning rehabilitation services to manage these symptoms appropriately and maximise the functional return of COVID-19 survivors.|
|Huang Y||10.1186/s12931-020-01429-6||2020||China||N/R||To investigate the influence of COVID-19 on lung function in early convalescence phase (at 30 days after discharged)||Descriptive: Historical cohort||N/A||Epidemiology - Natural history/Determining and modifying factors||Respiratory structures (s430) and related functions (Respiration b440-455)||Post-acute||COVID-19||57||N/A||N/A||N/A||Lung volumes (TLC), spirometry (FVC, FEV1), DLCO, ,respiratory muscle strength, 6-MWT and high resolution CT||N/A||N/A||N/A||N/A||N/A||N/A||Out of 57 COVID-19 patients, 40 were non-severe and 17 were severe ones. Impaired diffusing-capacity, respiratory muscle strength decrease, and lung imaging abnormalities were detected in more than half of the COVID-19 patients in the early convalescence phase. Compared with non-severe cases, severe patients had a higher incidence of DLCO impairment (75.6% vs 42.5%) and encountered more TLC decrease and 6MWT decline. Tha authors showed that most of the COVID-19 patients had a pulmonary function impairment in early convalescence phase, concluding that there is a need of longer follow-up studies in COVID-19 patients to better investigate clinical outcomes (i.e. tendency of lung function and exercise tolerance) in recovered COVID-19 patients.|
|Khalifa M||10.1093/jpids/piaa086||2020||Saudi Arabia||From 10th of April, 2020||To report one of the first descriptions of GBS and COVID-19 association in a child||Descriptive: Case Report||N/A||Epidemiology - Clinical presentation||Nervous system structures (s1) and related functions (Neuromusculoskeletal and movement related functions b7)||Acute||COVID-19 child developing GBS||1||After three weeks with mild febrile illness with mild respiratory manifestations and a persistent cough, a eleven-year-old boy presented with typical features of GBS and after five days a morbilliform skin rash over the palms of both hands.||-intravenous immunoglobulin (IVIG) infusions at a dose of 1 gram/kg/day for two days. -paracetamol when needed (10mg/kg/dose) - hydroxychloroquine twice daily (6.5 MG/KG) for one day, and then (3.25 MG/KG) twice daily for seven days. -as thromboprophylaxis low molecular weight heparin (R/ Enoxaparin) was given s.c.20 IU once daily.||N/A||Neurological assessment||N/A||N/A||N/A||N/A||N/A||N/A||This report describes an eleven-year-old boy, who presented with acute GBS, three weeks after a mild symptomatic respiratory illness (positive infection via nasopharyngeal RT-PCR). -Awareness of neuromuscular presentations also in children may have a guiding significance for the early detection of the combined or preceding infection with SARS-CoV-2|
|Kirshblum SC||10.1002/pmrj.12454||2020||USA||April 4th - 27th, 2020||To determine the prevalence of COVID-19 in asymptomatic individuals referred for admission to an inpatient rehabilitation facility in a high prevalence community setting||Descriptive: Historical cohort||General postacute rehabilitation||Epidemiology - Clinical presentation||N/A||Post-acute||Patients admitted to an inpatient rehabilitation facility and presumed to be COVID-19 free||103||N/A||N/A||N/A||Positivity at the reverse transcriptase-polymerase chain reaction SARS-COV-2 testing withing the first two weeks of admission||N/A||N/A||N/A||N/A||N/A||N/A||Seven patients resulted positive at SARS-COV-2 testing at admission (6.8%). Two positive patients stayed asymptomatic while five developed symptoms in the next 5.2 days. Nine patients who tested negative were subsequently re-tested for developing symptoms compatible with COVID-19 infection, and five of them resulted positive. Overall, 12 patients (13.6%) resulted positive in the first 14 days of hospitalization. Screening for SARS-CoV-2 at the time of admission to an inpatient rehabilitation facility can identify pre-symptomatic or asymptomatic individuals, to determine their appropriate placement within a facility and using appropriate infection control practices. However, negative results do not preclude COVID-19 and should not be used as the sole basis for patient management decisions.|
|Krett JD||10.1016/j.jneuroim.2020.577326||2020||Canada||N/R||To report a critically ill man with a COVID-19-associated hemorrhagic encephalopathy||Descriptive: Case Report||N/A||Epidemiology - Clinical presentation||Nervous system structures (s1) and related functions (Mental functions b1)||Acute||COVID-19 patient||1||Cough and fatigue and after 2 days increasing confusion. -At Hospital admission, the patient was disoriented, agitated, without lateralizing neurological deficits. -13 days later, the patient was unresponsive and diffusely paretic. -2 months following admission, the patient gradually recovered.||Mechanical ventilation, minimal vasopressor support, oral hydroxychloroquine, and neurorehabilitation||N/A||Neurological assessment, CSF analyses, brain MRI||N/A||N/A||N/A||N/A||N/A||N/A||This case reports encephalopathy with multifocal cerebral hemorrhages in a COVID-19 patient with severe, otherwise unexplained cortical dysfunction.
SARS-CoV-2 RNA was not detected in cerebrospinal fluid (CSF) or blood. CSF analyses suggested a cytokine release syndrome. Two months following hospital admission, the patient gradually recovered. He was transferred to a neurorehabilitation unit with mild residual physical and cognitive impairments.
Awareness of this clinical entity may facilitate the identification of patients with a potentially remediable cause of encephalopathy in COVID-19.
|Kushlaf H||10.1002/mus.27020||2020||USA||N/R||To report the clinical course of a patient with myasthenia gravis who developed COVID-19||Descriptive: Case Report||N/A||Epidemiology - Natural history/Determining and modifying factors||Nervous system structures (s1) and related functions (Neuromusculoskeletal and movement related functions b7)||Acute, post-acute, late-onset, or permanent on a pre-existing health condition||Patient with myasthenia gravis developing COVID-19||1||The patient presented with fever and SOB||Hydroxychloroquine for 5 days, tocilizumab, and IVIG 1 g/kg daily for two consecutive days.||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||A 66-year-old woman, who was diagnosed with myastenia gravis at age 44, was intubated for hypoxemic respiratory failure and she also presented with hypotension and acute renal failure for which she was placed on continuous renal replacement therapy followed by intermittent emodialysis. After the COVID-19 treatament, she slowly improved and was extubated after 17 days then discharged to inpatient rehabilitation.|
|Li Z||10.23736/S1973-9087.20.06298-X||2020||China||February 29th - March 2nd, 2020||To collect the basic information, dysfunctions, and rehabilitation needs of hospitalized COVID-19 patients.||Analytical: Cross-sectional study||N/A||Epidemiology - Prevalence||Respiratory structures (s430) and related functions (Respiration b440-455)||Post-acute||Post-acute hospitalized COVID-19 patients||280||N/A||A questionnaire that included demographic and clinical history of the patients, the awareness about rehabilitation and the willingness to do it, current dysfunctions they suffer from, and the specific needs for rehabilitation, was administered to all the patients included.||N/A||Awareness and willingness of rehabilitation; common dysfunctions; current rehabilitation needs||N/A||N/A||N/A||N/A||The average Content Validity Index of the questionnaire was 0.958. Cronbach’s alpha was used to assess the internal consistency reliability, which was found to be 0.944 .||N/A||Patients were 51.8% male and 48.2% females. 64.2% of the patients were over 51 years of age, and only 9.3 % below 30 years of age. The most common physical dysfunctions reported by the patients were sleep disorders (63.6%), decreased activity endurance (61.4%), respiratory dysfunction (57.9%), loss of appetite (55.4%), and pain disorder (47.5%). Meanwhile, the most reported psychological dysfunctions were anxiety (62.1%), fear (50.0%), apathy (41.8%), depression (40.7%), and despair (32.5%). The patients felt a high demand for rehabilitation: the sum of the high need and need response with regard to exercise guidance, dietary instruction, and traditional Chinese medicine therapy, were 45.0%, 40.4%, and 39.6%, respectively|
|Manganotti P||10.1002/jmv.26289||2020||Italy||March-April 2020||To report a case series of 5 COVID-19 patients who developed GBS||Descriptive: Case Series||N/A||Epidemiology - Natural history/Determining and modifying factors||Acute||COVID-19 patients developing GBS||5||Fever and cough, and a significant impairment of taste and smell in 4/5 patients. The patients developed progressive weakness of the upper and lower limbs, in a disto-proximal fashion with a latency ranging from 14 to 30 days.||IVIG therapy was initiated in 4/5 patients at a dose of 0.4 gr/kg for 5 days.||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||Four out 5 COVID-19 patients with GBS presented with a mild facial nerve involvement limited to the muscles of the lower face; in one patient, taste assessment showed right-sided ageusia of the tongue, ipsilateral to the mild facial palsy. The Authors report that peripheral nervous system involvement after COVID-19 might be successfully treated with IVIG, as showed in 4/5 patients, whose neurological symptoms partially resolved without any side effect.|
|Ng JA||10.1093/ptj/pzaa124||2020||USA||April - May, 2020||To describe the establishment, operation and evolution of a rehabilitation therapist staffed prone team.||Descriptive: Historical cohort||Rehabilitation in acute care||Meso Level||Respiratory structures (s430) and related functions (Respiration b440-455)||Acute||COVID-19 patients in need of prone positioning||934||N/A||Position change by a prone team.||N/A||Number of position changes in a 7 weeks period, time spent for each position change, number of members of the team needed for each position change.||N/A||N/A||N/A||N/A||N/A||N/A||With the surge of ARDS cases due to COVID-19, the request for proning position increased exponentially. Given the possible side effect of prone positioning, and the complexity of the procedure, a team of rehabilitation therapists expert of mobilisation is needed to improve the outcome of patients. The team achieved during the pandemic the following numbers and goals. Total volume of requests to the prone team for position changes was 934. 70% of position changes involved 3 prone team members, 26% involved 2, 13% involved only 1 and 11% involved 4. The mean (SD) number of minutes for each position change was 20 (9.15) with a range of 5 to 80 minutes.|
|Pfefferkorn T||10.1007/s00415-020-09897-y||2020||Germany||April 2020||To report the case of a COVID-19 patient presenting with acute polyradiculoneuritis.||Descriptive: Case Report||N/A||Epidemiology - Natural history/Determining and modifying factors||Acute||COVID-19 patient||1||Fever, cough, tetraparesis and acral paresthesias.||Mechanical ventilation, tracheostomy, intravenous immunoglobulins, plasma exchange therapy.||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||The authors report the case of a 52 years old man who presented with tetraparesis after 14 days of fever and respiratory symptoms and was found positive on COVID-19 testing. The patient underwent mechanical ventilation and tracheostomy, and IVIG and plasma exchange therapy were administred. Thirty-one days after admission the patient showed signs of motor improvement with regressive facial and hypoglossal paresis but still needed mechanical ventilation, and was referred to a specialized rehabilitation clinic.|
|Piscitelli D||10.1007/s10072-020-04593-1||2020||Italy||March 5th - May 13th,2020||To report the case of a 39-year-old woman, in- home nurse, of normal social well-being with no history of somatoform or other psychiatric disorder or traumas, who developed, with SARS-CoV-2 infection, functional tremors.||Descriptive: Case Report||N/A||Epidemiology - Natural history/Determining and modifying factors||Nervous system structures (s1) and related functions (Mental functions b1)||Acute||COVID-19 patient||1||After 7 days with mild COVID-19 symptoms the patient developed a lower limb tremor with variable frequency and amplitude. She presented abnormal movements while sitting (e.g., lower limb twisted movements), walking (e.g., ataxic gait), or at rest (e.g., jerky movements in supine position)||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||Case report of a patient without any history of psychiatric/neurologic events.
|Rosen K||10.1007/s11420-020-09774-4||2020||USA||April 8th - May 12th, 2020||To investigate if an inpatient telerehabilitation program was viable for COVID-19 patients.||Descriptive: Historical cohort||Rehabilitation in acute care||Meso Level||Respiratory structures (s430) and related functions (Respiration b440-455)||Post-acute||COVID-19 patients||33 (12 of whom received only telerehabilitation PT services)||N/A||Telerehabilitation||In person PT or Telerehabilitation PT + in person PT||Percentage of patient that met their PT goals and were discharged.||N/A||N/A||N/A||N/A||N/A||N/A||The Hospital for Special Surgery in New York city, due to COVID-19 outbreak, introduced a telerehabilitation service for COVID-19 patients, based on a COVID-19 rehabilitation response algorithm. This latter could identify 3 groups:
|Saggese CE||10.1159/000509453||2020||Italy||March - April, 2020||To present the case of a COVID-19 patient presenting with stroke and thromboses in different locations||Descriptive: Case Report||N/A||Epidemiology - Clinical presentation||Acute||COVID-19 patient presenting with stroke||1||Expressive aphasia, right hemiplegia, right neglect occurring after ten days of fever and cough.||rTPA therapy, oxygen, clopidogrel, atorvastatin, hydroxychloroquine, azithromycin, enoxaparin, amlodipine and ramipril.||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||The paper describe the case of an acute ischemic stroke patient who was suffering from fever and cough since ten days and was found positive for COVID-19 on admission. Afterwards he developed right dorsalis pedis and distal lateral plantar artery occlusion that were recanalized with balloon catheter, and left forearm superficial thrombophlebitis. The authors underline that although this was not a severe case of COVID-19, the ischemic vascular complications may have been linked to the COVID-19 infection.|
|Shalash A||10.1002/mds.28134||2020||Egypt||N/R||To investigate the impact of the COVID-19 pandemic on the mental health, physical activities, and QoL of PD patients.||Analytical: Cross-sectional study||N/A||Epidemiology - Prevalence||N/A||N/A||PD patients||58 (38 PD, 20 no PD)||N/A||telephone interview||Age- and sex-matched controls without PD||perception of impact of COVID-19, DASS-21, IPAQ, PDQ39||N/A||N/A||N/A||N/A||N/A||N/A||Compared with controls, PD patients showed significantly worse stress, depression, anxiety, total DASS, moderate physical activity, walking, total IPAQ, total and most of the PDQ39 dimensions, which were correlated with current mental health and pre- lockdown characteristics (i.e. motor severity).
|Tankisi H||10.1016/j.clinph.2020.06.003||2020||Denmark||March - April, 2020||To describe the case of a COVID-19 patient who developed critical illness myopathy||Descriptive: Case Report||N/A||Epidemiology - Natural history/Determining and modifying factors||Acute||COVID-19 patient||1||Severe symmetrical proximal and distal weakness, diffuse muscle wasting, and absent deep tendon reflexes occurring 10 days after COVID-19 infection onset with fever, cough, dyspnea||Piperacillin/tazobactam, oxygen, mechanical ventilation||N/A||N/A||N/A||N/A||N/A||N/A||N/A||N/A||The authors describe the case of a severe COVID-19 patient that needed mechanical ventilation and ICU stay. After 65 days of hospitalization the patient presented severe muscle weakness. Electromyography analysis revealed critical illness myopathy. This is the first case of CIM in a patient surviving from severe COVID-19. While clinical and electrophysiological findings resembled CIM of other causes, this case deserves special attention in the context of a growing awareness of long-term complications of COVID-19.|
|Tay SS||N/A||2020||Singapore||March - April, 2020||To describe the case of a COVID-19 patients who benefitted from the use of a robotic patient-guided suspension system for mobilisation.||Descriptive: Case Report||Specialized postacute rehabilitation||Micro - Interventions (efficacy/harms)||Any Activity limitation and participation restriction (d)||Post-acute||COVID-19 patient||1||The patient presented, cough, dyspnea and respiratory failure on admission to acute care||Conventional physiotherapy and occupational therapy, gait training with the Andago V2.0 robot (Hocoma) which is a dynamic patient-guided suspension system for overground walking.||N/A||HADS-A, HADS-D, 6MWT||N/A||N/A||N/A||N/A||N/A||N/A||A severe COVID-19 patient after ICU discharge presented depression and anxiety and severe impairment in gait autonomy and endurance. After conventional physical therapy and training with robotic patient-guided suspension system the patient was able to walk significantly longer in the 6MWT and had lower score in HADS-A and D. The robotic system seemed safe and efficient for recovering gait autonomy in the patient presented.|
|Tiet MY||10.1136/bcr-2020-236536||2020||UK||N/R||To report a case of GBS associated with COVID-19||Descriptive: Case Report||N/A||Epidemiology - Natural history/Determining and modifying factors||Post-acute||COVID-19 patient developing GBS||1||He reported a 3-week history of shortness of breath, headache and cough. -Then, he showed worsening cough and distal lower limb paraesthesia, resulting in difficulty mobilising. -3 days after being discharged home there was worsening lower limb paraesthesia and ascending lower limb weakness. -4 days later, he developed facial diplegia, limbs weakness (MRC: 1/5 in lower limbs, 3/5 proximal upper limbs and 2/5 distal upper limbs), distal reduced sensation to pinprick and vibration sense, dysaesthesia in lower limbs, and he was areflexic.||Monitoring in intensive care -nasogastric tube for feeding due to swallowing difficulties -intravenous immunoglobulin 0.4 g/kg daily for 5 days -neurorehabilitation||N/A||Neurological assessment, SARS-CoV-2 PCR in cerebrospinal fluid and from oropharyngeal swabs||N/A||N/A||N/A||N/A||N/A||N/A||The patient developed GBS as a likely postinfectious complication 3 weeks after the onset of mild COVID-19 related symptoms.
|Zhao Y-M||10.1016/j.eclinm.2020.100463||2020||China||January 20th - February 24th, 2020||To study the pulmonary function, HRCT scan of the thorax and SARS-CoV-2 IgG in serum in COVID-19 patients 3 months after their hospital discharged and to investigate the relationship between the clinical characteristics and the pulmonary function or CT scores.||Descriptive: Historical cohort||N/A||Epidemiology - Natural history/Determining and modifying factors||Respiratory structures (s430) and related functions (Respiration b440-455)||Chronic||COVID-19 survivors||55||Of 55 patients, including 4 mild (7.27%), 47 moderate (85.45%) and 4 severe (7.27%) cases, 35 presented COVID-19 related symptoms including gastrointestinal symptoms (30.91%), headache (18.18%), fatigue (16.36%), exertional dyspnea (14.55%), as well as cough and sputum (1.81%). Of the 55 patients, 6 experienced olfactory and gustatory dysfunctions during infection period and 2 female still experienced a decrease sense of taste during follow-up period.||pulmonary function test||Clinical assessment, HRCT of the thorax, lung function and serum levels of SARS-CoV-2 IgG antibody tests 3 months after discharge||N/A||N/A||N/A||N/A||N/A||N/A||3 months after discharge COVID-19 symptoms were detected in 35/55 patients and different degrees of radiological abnormalities were detected in 39 patients.