The WHO – Cochrane rehabilitation Be4rehab (Best Evidence for Rehabilitation) project, during this year, has advanced towards its goal of extracting data from:
- Clinical Practice Guidelines (CPGs)
- Cochrane Systematic Reviews (CSRs)
to inform the Package of Interventions in Rehabilitation (PIR).
Cochrane Rehabilitation was mainly responsible for two tasks:
(1) to supervise the methodology of the 8 Technical Working Groups (TWGs) that had the aim to extract the recommendations from CPGs relevant to rehabilitation for a specific health condition,
(2) to extract the data from all the 245 CSRs related to 17 out of the 20 health conditions that had been included in the PIR.
As per the first task, all 8 TWGs completed their assignment; data from 59 CPGs were extracted and information was sent to WHO selected multi-professional panels.
The data extraction from CSRs was completed for 16 health conditions. A total of 220 reviews were assessed. 133 of these CSRs included a Summary of Findings table complete with evidence quality evaluation according to GRADE system. The remaining 68 did not present a GRADE evaluation: for 48 a Summary of Findings and GRADE assessment were prepared; the remaining 20 either were empty reviews (6), focused only on secondary outcomes (2), presented only a descriptive summary (10) or were overviews (2).
Negrini S, Arienti C, Patrini M, Kiekens C, Rauch A, Cieza A. Cochrane collaborates with the World Health Organization to establish a Package of Rehabilitation Interventions based on the best available evidence. Eur J Phys Rehabil Med. 2021 Jun;57(3):478-480. doi: 10.23736/S1973-9087.21.07075-1. PubMed link
Rauch A, Negrini S, Cieza A. Author Response to "WHO Package of Rehabilitation Interventions: Some Concerns About Methodology". Arch Phys Med Rehabil. 2020 Jun;101(6):1095-1096. doi: 10.1016/j.apmr.2020.01.006. PubMed link
Rauch A, Negrini S, Cieza A. Toward Strengthening Rehabilitation in Health Systems: Methods Used to Develop a WHO Package of Rehabilitation Interventions. Arch Phys Med Rehabil. 2019 Nov;100(11):2205-2211. doi: 10.1016/j.apmr.2019.06.002. PubMed link
Zaina F, Côté P, Cancelliere C, Di Felice F, Donzelli S, Rauch A, Verville L, Negrini S, Nordin M. A Systematic Review of Clinical Practice Guidelines for Persons With Non-specific Low Back Pain With and Without Radiculopathy: Identification of Best Evidence for Rehabilitation to Develop the WHO's Package of Interventions for Rehabilitation. Arch Phys Med Rehabil. 2023 Mar 23:S0003-9993(23)00160-0. doi: 10.1016/j.apmr.2023.02.022. PMID: 36963709. PubMed link
Oral A, Arman S, Tarakci E, Patrini M, Arienti C, Etemadi Y, Rauch A, Negrini S. A systematic review of clinical practice guidelines for persons with osteoarthritis. A "Best Evidence for Rehabilitation" (be4rehab) paper to develop the WHO's Package of Interventions for Rehabilitation: A systematic review of Clinical Practice Guidelines for persons with osteoarthritis for the identification of best evidence for rehabilitation. Int J Rheum Dis. 2022 Apr;25(4):383-393. doi: 10.1111/1756-185X.14292. PubMed link
Gimigliano F, Liguori S, Moretti A, Toro G, Rauch A, Negrini S, Iolascon G; Technical Working Group. A systematic review of Clinical Practice Guidelines for the management of fractures in children to develop the WHO's Package of Interventions for Rehabilitation. Eur J Phys Rehabil Med. 2022 Apr;58(2):236-241. doi: 10.23736/S1973-9087.21.06916-1. PubMed link
Heyns A, Jacobs S, Negrini S, Patrini M, Rauch A, Kiekens C. Systematic Review of Clinical Practice Guidelines for Individuals With Amputation: Identification of Best Evidence for Rehabilitation to Develop the WHO's Package of Interventions for Rehabilitation. Arch Phys Med Rehabil. 2021 Jun;102(6):1191-1197. doi: 10.1016/j.apmr.2020.11.019. PubMed link
Gimigliano F, Liguori S, Moretti A, Toro G, Rauch A, Negrini S; other members of the Technical Working Group, Iolascon G. Correction to: Systematic review of clinical practice guidelines for adults with fractures: identification of best evidence for rehabilitation to develop the WHO's Package of Interventions for Rehabilitation. J Orthop Traumatol. 2021 Mar 1;22(1):7. doi: 10.1186/s10195-021-00566-y. Erratum for: J Orthop Traumatol. 2020 Nov 14;21(1):20. PMID: 33649874; PMCID: PMC7921260. PubMed link
Liguori S, Young VM, Arienti C, Pollini E, Patrini M, Gimigliano F, Negrini S, Kiekens C. Overview of Cochrane systematic reviews for rehabilitation interventions in individuals with cerebral palsy: A mapping synthesis. Dev Med Child Neurol. 2023 Mar 12. doi: 10.1111/dmcn.15572. PubMed link
Küçükdeveci AA, Turan BK, Arienti C, Negrini S. Overview of Cochrane Systematic Reviews of rehabilitation interventions for persons with rheumatoid arthritis: a mapping synthesis. Eur J Phys Rehabil Med. 2023 Feb 2. doi: 10.23736/S1973-9087.22.07833-9. PubMed link
Zampogna E, Ferriero G, Visca D, Patrini M, Negrini S, Arienti C. An Overview of Cochrane Systematic Reviews for pulmonary rehabilitation interventions in people with COPD: a mapping synthesis. Panminerva Med. 2022 Jul 29. doi: 10.23736/S0031-0808.22.04757-7. PubMed link
Arienti C, Patrini M, Negrini S, Kiekens C. Overview of Cochrane Systematic Reviews for Rehabilitation Interventions in Persons With Spinal Cord Injury: A Mapping Synthesis. Arch Phys Med Rehabil. 2022 Jul 26:S0003-9993(22)00530-5. doi: 10.1016/j.apmr.2022.07.003. PubMed link
Young VM, Hill JR, Patrini M, Negrini S, Arienti C. Overview of Cochrane Systematic Reviews of Rehabilitation Interventions for Persons with Traumatic Brain Injury: A Mapping Synthesis. J Clin Med. 2022 May 10;11(10):2691. doi: 10.3390/jcm11102691. PubMed link